Linker Information
General Information of This Linker
| Linker ID |
LIN0ZNFFC
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Drug linker PB040
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Formula |
C38H55N7O13
|
|||||
| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCCNC(CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)=O)C(NC2=CC=C(C=C2)CO)=O)=O)C
|
|||||
| InChI |
InChI=1S/C38H55N7O13/c1-25(2)36(42-29(47)9-4-3-7-17-45-31(49)14-15-32(45)50)38(58)41-28(37(57)40-27-12-10-26(24-46)11-13-27)8-5-6-16-39-30(48)20-43(21-33(51)52)18-19-44(22-34(53)54)23-35(55)56/h10-15,25,28,36,46H,3-9,16-24H2,1-2H3,(H,39,48)(H,40,57)(H,41,58)(H,42,47)(H,51,52)(H,53,54)(H,55,56)/t28-,36-/m0/s1
|
|||||
| InChIKey |
JLHBFQVIUDMAJX-GOOPYHEFSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
817.894
|
Polar area
|
292.39
|
||
|
Complexity
|
1527.428701
|
xlogp Value
|
-0.6273
|
|||
|
Heavy Count
|
58
|
Rot Bonds
|
29
|
|||
|
Hbond acc
|
12
|
Hbond Donor
|
8
|
|||
Each Antibody-drug Conjugate Related to This Linker