General Information of This Linker
Linker ID
LIN0ZMWNW
Linker Name
TW202506738A-C-335-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C32H55N5O17S
Isosmiles
COCCOCCOCCOCCOCCOCCOCCOCCS(N(CCC(NCC(NCC(NCC(O)=O)=O)=O)=O)CCN1C(C=CC1=O)=O)(=O)=O
PubChem CID
169607889
InChI
InChI=1S/C32H55N5O17S/c1-47-8-9-48-10-11-49-12-13-50-14-15-51-16-17-52-18-19-53-20-21-54-22-23-55(45,46)36(6-7-37-30(41)2-3-31(37)42)5-4-27(38)33-24-28(39)34-25-29(40)35-26-32(43)44/h2-3H,4-26H2,1H3,(H,33,38)(H,34,39)(H,35,40)(H,43,44)
InChIKey
MPEWEVTVGACDST-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
813.877
Polar area
273.2
Complexity
1192.3128
xlogp Value
-3.8709
Heavy Count
55
Rot Bonds
37
Hbond acc
16
Hbond Donor
4
Each Antibody-drug Conjugate Related to This Linker