Linker Information
General Information of This Linker
| Linker ID |
LIN0ZLJDX
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|---|---|---|---|---|---|---|
| Linker Name |
Conjugate No.57 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H43N5O9
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| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCNC(CCN1C(CCC1=O)=O)=O)=O)C(N[C@H](C(O)=O)CCCCN)=O
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| InChI |
InChI=1S/C25H43N5O9/c1-17(2)23(24(35)28-18(25(36)37)5-3-4-10-26)29-20(32)9-13-38-15-16-39-14-11-27-19(31)8-12-30-21(33)6-7-22(30)34/h17-18,23H,3-16,26H2,1-2H3,(H,27,31)(H,28,35)(H,29,32)(H,36,37)/t18-,23-/m0/s1
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| InChIKey |
LQYQDDNYSTZSDF-MBSDFSHPSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
557.645
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Polar area
|
206.46
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Complexity
|
770.8559515
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xlogp Value
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-1.0958
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Heavy Count
|
39
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Rot Bonds
|
21
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker