Linker Information
General Information of This Linker
| Linker ID |
LIN0ZIRGV
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
CN119630431A-ADC-78-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C12H20N2O10P2
|
|||||
| Isosmiles |
O=C(N1CCCCCC(NCCOP(O)(OP(O)(O)=O)=O)=O)C=CC1=O
|
|||||
| InChI |
InChI=1S/C12H20N2O10P2/c15-10(13-7-9-23-26(21,22)24-25(18,19)20)4-2-1-3-8-14-11(16)5-6-12(14)17/h5-6H,1-4,7-9H2,(H,13,15)(H,21,22)(H2,18,19,20)
|
|||||
| InChIKey |
QFNRPVAHXVWPDL-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
414.244
|
Polar area
|
179.77
|
||
|
Complexity
|
598.4237513
|
xlogp Value
|
-0.1857
|
|||
|
Heavy Count
|
26
|
Rot Bonds
|
12
|
|||
|
Hbond acc
|
7
|
Hbond Donor
|
4
|
|||
Each Antibody-drug Conjugate Related to This Linker