Linker Information
General Information of This Linker
| Linker ID |
LIN0ZILCK
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|---|---|---|---|---|---|---|
| Linker Name |
WO2024105205A1-6e-1015-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C16H27N5O7
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| Isosmiles |
O=C(O)[C@@H](NC([C@H](C)N(C)C([C@H](C)NC(CCCC(N)=O)=O)=O)=O)CC(N)=O
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| InChI |
InChI=1S/C16H27N5O7/c1-8(19-13(24)6-4-5-11(17)22)15(26)21(3)9(2)14(25)20-10(16(27)28)7-12(18)23/h8-10H,4-7H2,1-3H3,(H2,17,22)(H2,18,23)(H,19,24)(H,20,25)(H,27,28)/t8-,9-,10-/m0/s1
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| InChIKey |
OMXQVHDLRBWTBW-GUBZILKMSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
401.42
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Polar area
|
201.99
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Complexity
|
597.5278502
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xlogp Value
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-2.5616
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Heavy Count
|
28
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Rot Bonds
|
12
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Hbond acc
|
6
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker