Linker Information
General Information of This Linker
| Linker ID |
LIN0ZIDEA
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|---|---|---|---|---|---|---|
| Linker Name |
MC-Ser-Cit-RG-1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H40N6O10
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| Isosmiles |
O=C(N[C@@H](CO)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C33H40N6O10/c1-21(35-27(41)10-4-3-7-17-39-28(42)15-16-29(39)43)30(44)37-25(19-40)31(45)36-24-13-11-22(12-14-24)20-49-32(46)34-18-23-8-5-6-9-26(23)38(2)33(47)48/h5-6,8-9,11-16,21,25,40H,3-4,7,10,17-20H2,1-2H3,(H,34,46)(H,35,41)(H,36,45)(H,37,44)(H,47,48)/t21-,25-/m0/s1
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| InChIKey |
XNJMQYJKKYPAHI-OFVILXPXSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
680.715
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Polar area
|
223.78
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Complexity
|
1483.264172
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xlogp Value
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1.6329
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Heavy Count
|
49
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Rot Bonds
|
17
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker