Linker Information
General Information of This Linker
| Linker ID |
LIN0ZIAQN
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| Linker Name |
Daratumumab-I-32-0.28 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C59H79FN10O18
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| Isosmiles |
CC(N[C@@H](CC1=CNC=N1)C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(NCCOCCNC(C3=CC=C(OC(CCOCCOCCOCCOCCOCCOCCN)=O)C(F)=C3)=O)=O)CC4=CNC5=C4C=CC=C5)=O)=O)CCC(O)=O)=O)=O
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| InChI |
InChI=1S/C59H79FN10O18/c1-39(71)67-51(35-43-37-62-38-66-43)59(80)68-48(11-13-53(73)74)57(78)69-49(32-40-6-9-44(72)10-7-40)58(79)70-50(34-42-36-65-47-5-3-2-4-45(42)47)56(77)64-17-21-83-20-16-63-55(76)41-8-12-52(46(60)33-41)88-54(75)14-18-81-22-24-84-26-28-86-30-31-87-29-27-85-25-23-82-19-15-61/h2-10,12,33,36-38,48-51,65,72H,11,13-32,34-35,61H2,1H3,(H,62,66)(H,63,76)(H,64,77)(H,67,71)(H,68,80)(H,69,78)(H,70,79)(H,73,74)/t48-,49-,50-,51-/m0/s1
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| InChIKey |
MTJFLQJKOMJXMQ-KBQHETQHSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1235.331
|
Polar area
|
393.53
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Complexity
|
2838.497346
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xlogp Value
|
0.5041
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Heavy Count
|
88
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Rot Bonds
|
45
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Hbond acc
|
19
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker