Linker Information
General Information of This Linker
| Linker ID |
LIN0ZFZAH
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|---|---|---|---|---|---|---|
| Linker Name |
Maleimide linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C11H15N3O3
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| Isosmiles |
[H][C@]12CCC3=C(N=NN3)CC[C@@]1([H])[C@H]2COC(O)=O
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| InChI |
InChI=1S/C11H15N3O3/c15-11(16)17-5-8-6-1-3-9-10(13-14-12-9)4-2-7(6)8/h6-8H,1-5H2,(H,15,16)(H,12,13,14)/t6-,7+,8-
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| InChIKey |
YIOOZMXCOHPCOX-RNLVFQAGSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
237.259
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Polar area
|
88.1
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Complexity
|
380.9277304
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xlogp Value
|
1.2403
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Heavy Count
|
17
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Rot Bonds
|
2
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Hbond acc
|
4
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker