Linker Information
General Information of This Linker
| Linker ID |
LIN0ZETHN
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|---|---|---|---|---|---|---|
| Linker Name |
TWI857167B-IC-90-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H46F4O17S
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| Isosmiles |
FC1=C(F)C(OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)=C(F)C(F)=C1S(=O)(O)=O
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| InChI |
InChI=1S/C30H46F4O17S/c31-25-27(33)30(52(38,39)40)28(34)26(32)29(25)51-24(37)2-4-42-6-8-44-10-12-46-14-16-48-18-20-50-22-21-49-19-17-47-15-13-45-11-9-43-7-5-41-3-1-23(35)36/h1-22H2,(H,35,36)(H,38,39,40)
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| InChIKey |
HYTFUBRAEZPMEG-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
786.74
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Polar area
|
210.27
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Complexity
|
1141.875544
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xlogp Value
|
1.4259
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Heavy Count
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52
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Rot Bonds
|
35
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Hbond acc
|
15
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker