General Information of This Linker
Linker ID
LIN0ZDPNU
Linker Name
TW202506738A-C-325-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C37H64N4O16
Isosmiles
COCCOCCOCCOCCOCCOCCOCCOCCOCC(NCCCC[C@H](NC(CCCN1C(C=CC1=O)=O)=O)C(NCCCC(O)=O)=O)=O
PubChem CID
162720751
InChI
InChI=1S/C37H64N4O16/c1-49-14-15-50-16-17-51-18-19-52-20-21-53-22-23-54-24-25-55-26-27-56-28-29-57-30-33(43)38-11-3-2-6-31(37(48)39-12-4-8-36(46)47)40-32(42)7-5-13-41-34(44)9-10-35(41)45/h9-10,31H,2-8,11-30H2,1H3,(H,38,43)(H,39,48)(H,40,42)(H,46,47)/t31-/m0/s1
InChIKey
AHPLQULBCOUAES-HKBQPEDESA-N
Pharmaceutical Properties
Molecule Weight
820.931
Polar area
245.05
Complexity
1059.317538
xlogp Value
-0.7769
Heavy Count
57
Rot Bonds
41
Hbond acc
15
Hbond Donor
4
Each Antibody-drug Conjugate Related to This Linker