Linker Information
General Information of This Linker
| Linker ID |
LIN0ZARRT
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| Linker Name |
TWI857167B-IC-61-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C16H18F4O7
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| Isosmiles |
O=C(O)CCOCCOCCOCCC(OC1=C(F)C(F)=CC(F)=C1F)=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C16H18F4O7/c17-10-9-11(18)15(20)16(14(10)19)27-13(23)2-4-25-6-8-26-7-5-24-3-1-12(21)22/h9H,1-8H2,(H,21,22)
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| InChIKey |
FNFSPKVRQCEFPE-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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398.305
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Polar area
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91.29
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Complexity
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576.7045924
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xlogp Value
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2.063
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Heavy Count
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27
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Rot Bonds
|
13
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Hbond acc
|
6
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker