Linker Information
General Information of This Linker
| Linker ID |
LIN0YZDWJ
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| Linker Name |
CN119630431A-ADC-56-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C60H84N6O19S2
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCC(NCCCC[C@@H](C(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)NC(CCOCCOCCN2C(C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C2=O)=O)=O)=O
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| InChI |
InChI=1S/C60H84N6O19S2/c1-76-27-28-80-33-34-82-37-38-84-41-42-85-40-39-83-36-35-81-32-30-77-24-20-51(67)61-22-12-11-19-49(57(72)62-44-53(69)65-50(58(73)63-45-54(70)71)43-46-13-5-2-6-14-46)64-52(68)21-25-78-29-31-79-26-23-66-59(74)55(86-47-15-7-3-8-16-47)56(60(66)75)87-48-17-9-4-10-18-48/h2-10,13-18,49-50H,11-12,19-45H2,1H3,(H,61,67)(H,62,72)(H,63,73)(H,64,68)(H,65,69)(H,70,71)/t49-,50-/m0/s1
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| InChIKey |
VOWBGUJOALZJRT-WLTNIFSVSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1257.489
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Polar area
|
312.48
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Complexity
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2334.274369
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xlogp Value
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2.5432
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Heavy Count
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87
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Rot Bonds
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52
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Hbond acc
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20
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker