Linker Information
General Information of This Linker
| Linker ID |
LIN0YWZDR
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|---|---|---|---|---|---|---|
| Linker Name |
T-132 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H46N6O15
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| Isosmiles |
CN(CCOCCN(N=N1)C=C1COCCOCCNCCOCCN2C(C=CC2=O)=O)C(C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)C(O)[C@H](O4)C(O)=O)C(O)=C3)=O
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| InChI |
InChI=1S/C33H46N6O15/c1-37(31(46)21-2-3-24(23(40)18-21)53-33-29(45)27(43)28(44)30(54-33)32(47)48)8-13-51-14-9-38-19-22(35-36-38)20-52-17-16-50-12-7-34-6-11-49-15-10-39-25(41)4-5-26(39)42/h2-5,18-19,27-30,33-34,40,43-45H,6-17,20H2,1H3,(H,47,48)/t27-,28?,29+,30-,33+/m0/s1
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| InChIKey |
ZVCUCIPVVSDUQR-BBLVVYFMSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
766.758
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Polar area
|
274.03
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Complexity
|
1485.937173
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xlogp Value
|
-2.8921
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Heavy Count
|
54
|
Rot Bonds
|
24
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Hbond acc
|
18
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker