Linker Information
General Information of This Linker
| Linker ID |
LIN0YWVZA
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| Linker Name |
IG-L-44 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C61H83FN14O21
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| Isosmiles |
C[C@H](NC([C@@H](NC(CCC1=CC=C(N2C(C=CC2=O)=O)C(F)=C1OCCCC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)=O)C)=O)C(NC3=CC=C(C=C3)COC(O)=O)=O
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| InChI |
InChI=1S/C61H83FN14O21/c1-37(59(92)64-38(2)60(93)65-41-19-15-39(16-20-41)36-97-61(94)95)63-43(77)22-18-40-17-21-42(76-45(79)23-24-46(76)80)57(62)58(40)96-25-13-14-44(78)66(3)26-47(81)67(4)27-48(82)68(5)28-49(83)69(6)29-50(84)70(7)30-51(85)71(8)31-52(86)72(9)32-53(87)73(10)33-54(88)74(11)34-55(89)75(12)35-56(90)91/h15-17,19-21,23-24,37-38H,13-14,18,22,25-36H2,1-12H3,(H,63,77)(H,64,92)(H,65,93)(H,90,91)(H,94,95)/t37-,38-/m0/s1
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| InChIKey |
UTWOIEDKAUFWNQ-UWXQCODUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1367.41
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Polar area
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420.84
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Complexity
|
3216.311021
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xlogp Value
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-3.142
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Heavy Count
|
97
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Rot Bonds
|
36
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Hbond acc
|
19
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker