Linker Information
General Information of This Linker
| Linker ID |
LIN0YWLUJ
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| Linker Name |
Anti-Her2-AL1- LP9 LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H50N8O10
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| Isosmiles |
O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(O)=O)=O)=O)CNC(COC2CC(N=NN3CCOCCOCCOCCN)=C3CCCC2)=O
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| InChI |
InChI=1S/C33H50N8O10/c34-10-12-48-14-16-50-17-15-49-13-11-41-28-9-5-4-8-25(19-26(28)39-40-41)51-23-31(44)36-20-29(42)35-21-30(43)38-27(33(47)37-22-32(45)46)18-24-6-2-1-3-7-24/h1-3,6-7,25,27H,4-5,8-23,34H2,(H,35,42)(H,36,44)(H,37,47)(H,38,43)(H,45,46)/t25?,27-/m0/s1
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| InChIKey |
JTUVRFBYBPLSQY-GPNIZQGCSA-N
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| Pharmaceutical Properties |
Molecule Weight
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718.809
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Polar area
|
247.35
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Complexity
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1310.998865
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xlogp Value
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-1.8986
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Heavy Count
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51
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Rot Bonds
|
24
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Hbond acc
|
13
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker