Linker Information
General Information of This Linker
| Linker ID |
LIN0YWGDH
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
TWI857167B-IC-95-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C29H46F4O15S
|
|||||
| Isosmiles |
CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC1=C(F)C(F)=C(S(O)(=O)=O)C(F)=C1F)=O
|
|||||
| InChI |
InChI=1S/C29H46F4O15S/c1-2-38-5-6-40-9-10-42-13-14-44-17-18-46-21-22-47-20-19-45-16-15-43-12-11-41-8-7-39-4-3-23(34)48-28-24(30)26(32)29(49(35,36)37)27(33)25(28)31/h2-22H2,1H3,(H,35,36,37)
|
|||||
| InChIKey |
ULJGEDWRPVGQJN-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
742.731
|
Polar area
|
172.97
|
||
|
Complexity
|
1034.740908
|
xlogp Value
|
1.9711
|
|||
|
Heavy Count
|
49
|
Rot Bonds
|
33
|
|||
|
Hbond acc
|
14
|
Hbond Donor
|
1
|
|||
Each Antibody-drug Conjugate Related to This Linker