Linker Information
General Information of This Linker
| Linker ID |
LIN0YUYRU
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| Linker Name |
Anti-Her2-AL1- LP11 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H57N7O16
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| Isosmiles |
NCCOCCOCCOCCN(N=N1)C2=C1CC(OCC(NCCNC(C3=C(O[C@H](O4)[C@H](O)[C@@H](O)[C@H](O)[C@H]4CO)C=CC(COC(NCC(O)=O)=O)=C3)=O)=O)CCCC2
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| InChI |
InChI=1S/C37H57N7O16/c38-7-11-54-13-15-56-16-14-55-12-10-44-27-4-2-1-3-24(18-26(27)42-43-44)57-22-30(46)39-8-9-40-35(52)25-17-23(21-58-37(53)41-19-31(47)48)5-6-28(25)59-36-34(51)33(50)32(49)29(20-45)60-36/h5-6,17,24,29,32-34,36,45,49-51H,1-4,7-16,18-22,38H2,(H,39,46)(H,40,52)(H,41,53)(H,47,48)/t24?,29-,32-,33+,34-,36-/m1/s1
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| InChIKey |
NNQFXWRIPKWIJD-BCNNIJPDSA-N
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| Pharmaceutical Properties |
Molecule Weight
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855.896
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Polar area
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326.86
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Complexity
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1570.574677
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xlogp Value
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-3.0236
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Heavy Count
|
60
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Rot Bonds
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25
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Hbond acc
|
19
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker