Linker Information
General Information of This Linker
| Linker ID |
LIN0YRZSQ
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| Linker Name |
TW202506738A-C-333-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C39H67N5O17
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCC(NCCCC[C@@H](C(NCC(NCCCC(O)=O)=O)=O)NC(CCCN1C(C=CC1=O)=O)=O)=O
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| InChI |
InChI=1S/C39H67N5O17/c1-53-14-15-54-16-17-55-18-19-56-20-21-57-22-23-58-24-25-59-26-27-60-28-29-61-31-35(47)41-11-3-2-6-32(39(52)42-30-34(46)40-12-4-8-38(50)51)43-33(45)7-5-13-44-36(48)9-10-37(44)49/h9-10,32H,2-8,11-31H2,1H3,(H,40,46)(H,41,47)(H,42,52)(H,43,45)(H,50,51)/t32-/m0/s1
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| InChIKey |
GURLWIWSSDQHBF-YTTGMZPUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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877.983
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Polar area
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274.15
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Complexity
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1182.262704
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xlogp Value
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-1.6607
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Heavy Count
|
61
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Rot Bonds
|
43
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Hbond acc
|
16
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker