Linker Information
General Information of This Linker
| Linker ID |
LIN0YREOK
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|---|---|---|---|---|---|---|
| Linker Name |
WO2024105205A1-7e-1015-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C13H20N4O8
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| Isosmiles |
O=C(O)[C@@H](NC([C@H](CC(O)=O)NC(CCCC(N)=O)=O)=O)CC(N)=O
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| InChI |
InChI=1S/C13H20N4O8/c14-8(18)2-1-3-10(20)16-6(5-11(21)22)12(23)17-7(13(24)25)4-9(15)19/h6-7H,1-5H2,(H2,14,18)(H2,15,19)(H,16,20)(H,17,23)(H,21,22)(H,24,25)/t6-,7-/m0/s1
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| InChIKey |
PURAQIJGVXASAZ-BQBZGAKWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
360.323
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Polar area
|
218.98
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Complexity
|
526.2415647
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xlogp Value
|
-2.9537
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Heavy Count
|
25
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Rot Bonds
|
12
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Hbond acc
|
6
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker