Linker Information
General Information of This Linker
| Linker ID |
LIN0YNXXX
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| Linker Name |
CN112604004B-SCT-200-C-5-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H46N6O10
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| Isosmiles |
O=C(OCC1=CC=C(C=C1)NC(CNC([C@H](CC(C)C)NC(CNC(CNC(CC2CCC(CCN3C(C=CC3=O)=O)CC2)=O)=O)=O)=O)=O)O
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| InChI |
InChI=1S/C34H46N6O10/c1-21(2)15-26(33(47)37-19-29(43)38-25-9-7-24(8-10-25)20-50-34(48)49)39-30(44)18-36-28(42)17-35-27(41)16-23-5-3-22(4-6-23)13-14-40-31(45)11-12-32(40)46/h7-12,21-23,26H,3-6,13-20H2,1-2H3,(H,35,41)(H,36,42)(H,37,47)(H,38,43)(H,39,44)(H,48,49)/t22?,23?,26-/m0/s1
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| InChIKey |
RKIKWZBUPOIOQB-JGZAQREWSA-N
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| Pharmaceutical Properties |
Molecule Weight
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698.774
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Polar area
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229.41
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Complexity
|
1357.587817
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xlogp Value
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1.2108
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Heavy Count
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50
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Rot Bonds
|
18
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker