Linker Information
General Information of This Linker
| Linker ID |
LIN0YLSQQ
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|---|---|---|---|---|---|---|
| Linker Name |
WO2024140447A1 ADC 3 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H41BrN6O11
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| Isosmiles |
CC([C@H](NC(CNC(CCOCCOCCNC(CBr)=O)=O)=O)C(N[C@@H](C)C(NCC(NCOCC(O)=O)=O)=O)=O)C
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| InChI |
InChI=1S/C24H41BrN6O11/c1-15(2)22(24(39)30-16(3)23(38)28-11-19(34)29-14-42-13-21(36)37)31-20(35)12-27-17(32)4-6-40-8-9-41-7-5-26-18(33)10-25/h15-16,22H,4-14H2,1-3H3,(H,26,33)(H,27,32)(H,28,38)(H,29,34)(H,30,39)(H,31,35)(H,36,37)/t16-,22-/m0/s1
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| InChIKey |
GSNNLWDJNSGHAA-AOMKIAJQSA-N
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| Pharmaceutical Properties |
Molecule Weight
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669.527
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Polar area
|
239.59
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Complexity
|
843.264091
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xlogp Value
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-3.0264
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Heavy Count
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42
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Rot Bonds
|
23
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Hbond acc
|
10
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker