Linker Information
General Information of This Linker
| Linker ID |
LIN0YLQEU
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| Linker Name |
Tz-PEG4-EvcPAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C61H90N8O19
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| Isosmiles |
CC([C@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC(CC(C=C1)=CC=C1C(N=N2)=C3CCCCCC(OCC(NCCOCCOCCOCCN)=O)C3=C2C)=O)=O)CCC(O)=O)=O)C(CCC(NC4=CC=C(C=C4)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C61H90N8O19/c1-42(2)58(50(70)18-19-52(71)65-47-15-11-45(12-16-47)40-88-61(78)79)67-60(77)49(17-20-56(75)76)66-53(72)21-25-80-29-33-84-37-38-86-36-31-82-27-23-63-54(73)39-44-9-13-46(14-10-44)59-48-7-5-4-6-8-51(57(48)43(3)68-69-59)87-41-55(74)64-24-28-83-32-35-85-34-30-81-26-22-62/h9-16,42,49,51,58H,4-8,17-41,62H2,1-3H3,(H,63,73)(H,64,74)(H,65,71)(H,66,72)(H,67,77)(H,75,76)(H,78,79)/t49-,51?,58-/m0/s1
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| InChIKey |
QXVJQYFIMMNLGN-IIIAYBFESA-N
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| Pharmaceutical Properties |
Molecule Weight
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1239.428
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Polar area
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372.04
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Complexity
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2492.001798
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xlogp Value
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3.53912
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Heavy Count
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88
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Rot Bonds
|
46
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Hbond acc
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20
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker