Linker Information
General Information of This Linker
| Linker ID |
LIN0YLIYJ
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| Linker Name |
CN114450324B-ADC-41-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C95H150N6O37
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| Isosmiles |
O=C(CCNC(OCC(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)(NC(CCNC(OCC1C(C=CC=C2)=C2C3=CC=CC=C31)=O)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)NC(C(NCC(NC4=CC=C(COC(O)=O)C=C4)=O)=O)CC5=CC=CC=C5
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| InChI |
InChI=1S/C95H150N6O37/c1-110-24-26-112-28-30-114-32-34-116-36-38-118-40-42-120-44-46-122-48-50-124-52-54-126-56-58-128-60-62-130-64-66-132-68-70-134-76-95(101-89(103)21-23-96-92(106)136-75-86-84-14-8-6-12-82(84)83-13-7-9-15-85(83)86,78-138-93(107)97-22-20-88(102)100-87(72-79-10-4-3-5-11-79)91(105)98-73-90(104)99-81-18-16-80(17-19-81)74-137-94(108)109)77-135-71-69-133-67-65-131-63-61-129-59-57-127-55-53-125-51-49-123-47-45-121-43-41-119-39-37-117-35-33-115-31-29-113-27-25-111-2/h3-19,86-87H,20-78H2,1-2H3,(H,96,106)(H,97,107)(H,98,105)(H,99,104)(H,100,102)(H,101,103)(H,108,109)
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| InChIKey |
NPXOBRWITGCOTL-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1968.25
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Polar area
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479.57
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Complexity
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.
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xlogp Value
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4.2547
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Heavy Count
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138
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Rot Bonds
|
96
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Hbond acc
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36
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Hbond Donor
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7
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Each Antibody-drug Conjugate Related to This Linker