Linker Information
General Information of This Linker
| Linker ID |
LIN0YHJBL
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Antibody-drug conjugate (7)Linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C29H36N6O11
|
|||||
| Isosmiles |
OC(CNC([C@@H](CC1=CC=CC=C1)NC(CNC(CNC([C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)CC(O)=O)=O)=O)=O)=O)=O
|
|||||
| InChI |
InChI=1S/C29H36N6O11/c36-21(9-5-2-6-12-35-24(39)10-11-25(35)40)33-20(14-26(41)42)29(46)31-15-22(37)30-16-23(38)34-19(28(45)32-17-27(43)44)13-18-7-3-1-4-8-18/h1,3-4,7-8,10-11,19-20H,2,5-6,9,12-17H2,(H,30,37)(H,31,46)(H,32,45)(H,33,36)(H,34,38)(H,41,42)(H,43,44)/t19-,20+/m1/s1
|
|||||
| InChIKey |
FUADJXQHIFHQCR-UXHICEINSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
644.638
|
Polar area
|
257.48
|
||
|
Complexity
|
1270.503054
|
xlogp Value
|
-2.408
|
|||
|
Heavy Count
|
46
|
Rot Bonds
|
20
|
|||
|
Hbond acc
|
9
|
Hbond Donor
|
7
|
|||
Each Antibody-drug Conjugate Related to This Linker