Linker Information
General Information of This Linker
| Linker ID |
LIN0YGGXU
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| Name |
PSMA-HC41-LD9 LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H48N6O11
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| Isosmiles |
OCCOCCNCCN(C(OCC1=CC=C(C=C1)NC([C@H](NC([C@H](C(C)C)NC(OCCOCCN2C(C=CC2=O)=O)=O)=O)C)=O)=O)C
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| InChI |
InChI=1S/C32H48N6O11/c1-22(2)28(36-31(44)48-20-19-47-17-14-38-26(40)9-10-27(38)41)30(43)34-23(3)29(42)35-25-7-5-24(6-8-25)21-49-32(45)37(4)13-11-33-12-16-46-18-15-39/h5-10,22-23,28,33,39H,11-21H2,1-4H3,(H,34,43)(H,35,42)(H,36,44)/t23-,28+/m1/s1
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| InChIKey |
VRBKJZWXDLYLKS-LXFBAYGMSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
692.767
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Polar area
|
214.17
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Complexity
|
1194.99279
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xlogp Value
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-0.0109
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Heavy Count
|
49
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Rot Bonds
|
22
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Hbond acc
|
12
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker