Linker Information
General Information of This Linker
| Linker ID |
LIN0YFFTV
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| Linker Name |
LT4212552T-ADC-10-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H46N6O13
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| Isosmiles |
O=C(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
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| InChI |
InChI=1S/C33H46N6O13/c40-26(8-11-39-30(44)6-7-31(39)45)34-10-13-50-15-17-52-19-18-51-16-14-49-12-9-27(41)35-21-28(42)36-22-29(43)38-25(33(48)37-23-32(46)47)20-24-4-2-1-3-5-24/h1-7,25H,8-23H2,(H,34,40)(H,35,41)(H,36,42)(H,37,48)(H,38,43)(H,46,47)/t25-/m0/s1
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| InChIKey |
OJLHMFRYEWTMPD-VWLOTQADSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
734.76
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Polar area
|
257.1
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Complexity
|
1290.740346
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xlogp Value
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-2.9651
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Heavy Count
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52
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Rot Bonds
|
28
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker