Linker Information
General Information of This Linker
| Linker ID |
LIN0YCROX
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-009-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C17H19N3O5
|
|||||
| Isosmiles |
C[C@@H](C(NC1=CC=C(C=C1)O)=O)NC(CCCN2C(C=CC2=O)=O)=O
|
|||||
| InChI |
InChI=1S/C17H19N3O5/c1-11(17(25)19-12-4-6-13(21)7-5-12)18-14(22)3-2-10-20-15(23)8-9-16(20)24/h4-9,11,21H,2-3,10H2,1H3,(H,18,22)(H,19,25)/t11-/m0/s1
|
|||||
| InChIKey |
CTPDEYJOOAYRBM-NSHDSACASA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
345.355
|
Polar area
|
115.81
|
||
|
Complexity
|
663.253425
|
xlogp Value
|
0.5406
|
|||
|
Heavy Count
|
25
|
Rot Bonds
|
7
|
|||
|
Hbond acc
|
5
|
Hbond Donor
|
3
|
|||
Each Antibody-drug Conjugate Related to This Linker
