General Information of This Linker
Linker ID
LIN0YCROX
Linker Name
TW202506738A-C-009-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C17H19N3O5
Isosmiles
C[C@@H](C(NC1=CC=C(C=C1)O)=O)NC(CCCN2C(C=CC2=O)=O)=O
InChI
InChI=1S/C17H19N3O5/c1-11(17(25)19-12-4-6-13(21)7-5-12)18-14(22)3-2-10-20-15(23)8-9-16(20)24/h4-9,11,21H,2-3,10H2,1H3,(H,18,22)(H,19,25)/t11-/m0/s1
InChIKey
CTPDEYJOOAYRBM-NSHDSACASA-N
Pharmaceutical Properties
Molecule Weight
345.355
Polar area
115.81
Complexity
663.253425
xlogp Value
0.5406
Heavy Count
25
Rot Bonds
7
Hbond acc
5
Hbond Donor
3
Each Antibody-drug Conjugate Related to This Linker