Linker Information
General Information of This Linker
| Linker ID |
LIN0XYZIZ
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| Linker Name |
TW202506738A-C-109-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H47N7O19S
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| Isosmiles |
O=C(NCC(O)=O)CNC(CNC(CNC(CNC(CCN(S(=O)(CCOCOCOCOCOCOCOCOC)=O)CCN1C(C=CC1=O)=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C29H47N7O19S/c1-48-15-50-17-52-19-54-21-55-20-53-18-51-16-49-8-9-56(46,47)35(6-7-36-27(42)2-3-28(36)43)5-4-22(37)30-10-23(38)31-11-24(39)32-12-25(40)33-13-26(41)34-14-29(44)45/h2-3H,4-21H2,1H3,(H,30,37)(H,31,38)(H,32,39)(H,33,40)(H,34,41)(H,44,45)
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| InChIKey |
AJURXVWQLCGTMS-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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829.792
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Polar area
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331.4
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Complexity
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1329.991559
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xlogp Value
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-5.936
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Heavy Count
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56
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Rot Bonds
|
34
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Hbond acc
|
18
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker