Linker Information
General Information of This Linker (ID: LIN0XXJFW)
| Name |
Carbamic linkage linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Formula |
C33H47N4O16+
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| Isosmiles |
C[N+](CC1=CC(NC(CCNC(CCOCCOCCOCCN2C(C=CC2=O)=O)=O)=O)=C(C=C1)OC3[C@@H]([C@H]([C@@H]([C@@H](C(O)=O)O3)O)O)O)(C)CC(O)=O
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| InChI |
InChI=1S/C33H46N4O16/c1-37(2,19-27(42)43)18-20-3-4-22(52-33-30(46)28(44)29(45)31(53-33)32(47)48)21(17-20)35-24(39)7-9-34-23(38)8-11-49-13-15-51-16-14-50-12-10-36-25(40)5-6-26(36)41/h3-6,17,28-31,33,44-46H,7-16,18-19H2,1-2H3,(H3-,34,35,38,39,42,43,47,48)/p+1/t28-,29-,30+,31-,33?/m0/s1
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| InChIKey |
DBHXODLTWMHEFT-OMUAWHELSA-O
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| Pharmaceutical Properties |
Molecule Weight
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755.751
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Polar area
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277.02
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Complexity
|
1403.484755
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xlogp Value
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-2.5717
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Heavy Count
|
53
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Rot Bonds
|
23
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Hbond acc
|
14
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker