Linker Information
General Information of This Linker
| Linker ID |
LIN0XUXHP
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|---|---|---|---|---|---|---|
| Linker Name |
US20240269308A1 aHer2- (AL6-LP15)n Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C62H92N10O21
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| Isosmiles |
O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)CNC(CCOCCOCCNC(CN(CCOCCOCCOCCNC(COC2C#CCCCCC2)=O)CC(NCCOCCOCCC(NCC(NCC(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C62H92N10O21/c73-52(66-40-54(75)68-42-56(77)70-50(61(82)83)38-47-12-6-4-7-13-47)18-24-86-30-32-88-26-20-63-58(79)44-72(23-29-91-35-37-92-36-34-90-28-22-65-60(81)46-93-49-16-10-2-1-3-11-17-49)45-59(80)64-21-27-89-33-31-87-25-19-53(74)67-41-55(76)69-43-57(78)71-51(62(84)85)39-48-14-8-5-9-15-48/h4-9,12-15,49-51H,1-3,10,16,18-46H2,(H,63,79)(H,64,80)(H,65,81)(H,66,73)(H,67,74)(H,68,75)(H,69,76)(H,70,77)(H,71,78)(H,82,83)(H,84,85)/t49?,50-,51-/m0/s1
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| InChIKey |
BZTJGIPYQDDZNK-FHDXRQFTSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1313.467
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Polar area
|
413.58
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Complexity
|
2363.825111
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xlogp Value
|
-3.0249
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Heavy Count
|
93
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Rot Bonds
|
53
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Hbond acc
|
20
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker