Linker Information
General Information of This Linker
| Linker ID |
LIN0XUWHM
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|---|---|---|---|---|---|---|
| Linker Name |
D2 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C17H26N4O5
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| Isosmiles |
NOCC(N[C@@H](C(C)C)C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)C)=O)=O
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| InChI |
InChI=1S/C17H26N4O5/c1-10(2)15(21-14(23)9-26-18)17(25)19-11(3)16(24)20-13-6-4-12(8-22)5-7-13/h4-7,10-11,15,22H,8-9,18H2,1-3H3,(H,19,25)(H,20,24)(H,21,23)/t11-,15-/m0/s1
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| InChIKey |
LNYILEFCFSZGKN-NHYWBVRUSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
366.418
|
Polar area
|
142.78
|
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Complexity
|
584.9692549
|
xlogp Value
|
-0.3468
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Heavy Count
|
26
|
Rot Bonds
|
9
|
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Hbond acc
|
6
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker