Linker Information
General Information of This Linker
| Linker ID |
LIN0XUIPD
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| Linker Name |
CN116137818A-AbT-EXP12-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H40N6O13S
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC(CS(=O)(O)=O)=C(C=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C29H40N6O13S/c1-17(2)25(34-22(36)9-12-47-13-11-35-23(37)7-8-24(35)38)27(40)33-21(4-3-10-31-28(30)41)26(39)32-20-6-5-18(15-48-29(42)43)19(14-20)16-49(44,45)46/h5-8,14,17,21,25H,3-4,9-13,15-16H2,1-2H3,(H,32,39)(H,33,40)(H,34,36)(H,42,43)(H3,30,31,41)(H,44,45,46)/t21-,25-/m0/s1
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| InChIKey |
QVEUJUDVPJAIQG-OFVILXPXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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712.735
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Polar area
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289.93
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Complexity
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1457.887107
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xlogp Value
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-0.3867
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Heavy Count
|
49
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Rot Bonds
|
20
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker