Linker Information
General Information of This Linker
| Linker ID |
LIN0XPUVR
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| Linker Name |
CN113549127A-ADC-1-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H41N5O7S
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| Isosmiles |
CCCSC(CC1=O)C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CCCNC(N)=O)=O)=O)=O
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| InChI |
InChI=1S/C24H41N5O7S/c1-4-13-37-17-14-19(31)29(22(17)33)12-7-5-6-10-18(30)28-20(15(2)3)21(32)27-16(23(34)35)9-8-11-26-24(25)36/h15-17,20H,4-14H2,1-3H3,(H,27,32)(H,28,30)(H,34,35)(H3,25,26,36)/t16-,17?,20-/m0/s1
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| InChIKey |
STJYZZZAPQRZTL-CGOHPFHYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
543.687
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Polar area
|
188
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Complexity
|
771.8600238
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xlogp Value
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0.9762
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Heavy Count
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37
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Rot Bonds
|
18
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Hbond acc
|
7
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker