Linker Information
General Information of This Linker
| Linker ID |
LIN0XNOPK
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| Linker Name |
TW202506738A-C-186-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C18H27N3O3S2
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| Isosmiles |
C[C@H](NC(CCC(N(CCS)CCS)=O)=O)C(NC(C=C1)=CC=C1C)=O
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| InChI |
InChI=1S/C18H27N3O3S2/c1-13-3-5-15(6-4-13)20-18(24)14(2)19-16(22)7-8-17(23)21(9-11-25)10-12-26/h3-6,14,25-26H,7-12H2,1-2H3,(H,19,22)(H,20,24)/t14-/m0/s1
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| InChIKey |
CBCRJJXLYGBWHL-AWEZNQCLSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
397.566
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Polar area
|
78.51
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Complexity
|
566.5608032
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xlogp Value
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1.90662
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Heavy Count
|
26
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Rot Bonds
|
10
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Hbond acc
|
5
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker