Linker Information
General Information of This Linker
| Linker ID |
LIN0XNLKK
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| Linker Name |
T-8 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C44H69N3O26S
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| Isosmiles |
O=S(OC1=C(O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)C(O)=O)C=CC(C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)=C1)(O)=O
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| InChI |
InChI=1S/C44H69N3O26S/c48-35(5-8-47-36(49)3-4-37(47)50)45-6-9-60-11-13-62-15-17-64-19-21-66-23-25-68-27-29-70-30-28-69-26-24-67-22-20-65-18-16-63-14-12-61-10-7-46-42(54)32-1-2-33(34(31-32)73-74(57,58)59)71-44-40(53)38(51)39(52)41(72-44)43(55)56/h1-4,31,38-41,44,51-53H,5-30H2,(H,45,48)(H,46,54)(H,55,56)(H,57,58,59)/t38-,39+,40+,41-,44+/m0/s1
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| InChIKey |
DDFATBHAZVYRST-REWXVAQDSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1088.098
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Polar area
|
377.16
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Complexity
|
1820.606309
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xlogp Value
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-3.5171
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Heavy Count
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74
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Rot Bonds
|
45
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Hbond acc
|
24
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker