Linker Information
General Information of This Linker
| Linker ID |
LIN0XNCTI
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|---|---|---|---|---|---|---|
| Linker Name |
T-6 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H41N5O16S
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| Isosmiles |
O=S(OC1=C(O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)C=CC(C(N(CCOCCN3C=C(N=N3)COCCOCCN4C(CCC4=O)=O)C)=O)=C1)(O)=O
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| InChI |
InChI=1S/C29H41N5O16S/c1-32(6-9-45-10-7-33-15-19(30-31-33)17-47-13-12-46-11-8-34-23(36)4-5-24(34)37)28(41)18-2-3-20(21(14-18)50-51(42,43)44)48-29-27(40)26(39)25(38)22(16-35)49-29/h2-3,14-15,22,25-27,29,35,38-40H,4-13,16-17H2,1H3,(H,42,43,44)/t22-,25+,26+,27-,29-/m1/s1
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| InChIKey |
QEPIPXBYXOKDQA-IEDNFIQGSA-N
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| Pharmaceutical Properties |
Molecule Weight
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747.733
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Polar area
|
279.07
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Complexity
|
1501.083565
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xlogp Value
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-2.8906
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Heavy Count
|
51
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Rot Bonds
|
20
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Hbond acc
|
18
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker