Linker Information
General Information of This Linker
| Linker ID |
LIN0XKIMW
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| Linker Name |
CN119630431A-ADC-77-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C22H35N5O9
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| Isosmiles |
CC(C)[C@H](C(N[C@H](C(O)=O)CCCNC(N)=O)=O)NC(CCOCCOCCN1C(C=CC1=O)=O)=O
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| InChI |
InChI=1S/C22H35N5O9/c1-14(2)19(20(31)25-15(21(32)33)4-3-8-24-22(23)34)26-16(28)7-10-35-12-13-36-11-9-27-17(29)5-6-18(27)30/h5-6,14-15,19H,3-4,7-13H2,1-2H3,(H,25,31)(H,26,28)(H,32,33)(H3,23,24,34)/t15-,19+/m0/s1
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| InChIKey |
UHLYSPIOTUDLOO-HNAYVOBHSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
513.548
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Polar area
|
206.46
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Complexity
|
764.8559515
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xlogp Value
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-1.5066
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Heavy Count
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36
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Rot Bonds
|
18
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker