Linker Information
General Information of This Linker
| Linker ID |
LIN0XIOWS
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| Linker Name |
L5-P1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C51H79N11O21
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C(NC(CNC(OCC3=CN(N=N3)CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C51H79N11O21/c1-36(2)46(58-42(63)10-14-74-16-13-62-44(65)8-9-45(62)66)48(68)57-40(5-4-11-53-49(52)69)47(67)55-38-7-6-37(34-83-51(71)72)41(31-38)56-43(64)32-54-50(70)82-35-39-33-61(60-59-39)12-15-75-19-20-77-23-24-79-27-28-81-30-29-80-26-25-78-22-21-76-18-17-73-3/h6-9,31,33,36,40,46H,4-5,10-30,32,34-35H2,1-3H3,(H,54,70)(H,55,67)(H,56,64)(H,57,68)(H,58,63)(H,71,72)(H3,52,53,69)/t40-,46-/m0/s1
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| InChIKey |
QSYFUMHVHYYTHK-QBPIONHWSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1182.249
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Polar area
|
407.54
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Complexity
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2213.915189
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xlogp Value
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-0.5555
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Heavy Count
|
83
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Rot Bonds
|
47
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Hbond acc
|
23
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker