Linker Information
General Information of This Linker
| Linker ID |
LIN0XHOVW
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|---|---|---|---|---|---|---|
| Linker Name |
CN115364238B+Compound 4+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C21H33N5O7
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(NC(CCCNC(N)=O)C(O)=O)=O)C
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| InChI |
InChI=1S/C21H33N5O7/c1-13(2)18(19(30)24-14(20(31)32)7-6-11-23-21(22)33)25-15(27)8-4-3-5-12-26-16(28)9-10-17(26)29/h9-10,13-14,18H,3-8,11-12H2,1-2H3,(H,24,30)(H,25,27)(H,31,32)(H3,22,23,33)/t14?,18-/m0/s1
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| InChIKey |
WXNPFVBGHOJJLL-IBYPIGCZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
467.523
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Polar area
|
188
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Complexity
|
720
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xlogp Value
|
-0.3695
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Heavy Count
|
33
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Rot Bonds
|
15
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Hbond acc
|
6
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker
