Linker Information
General Information of This Linker
| Linker ID |
LIN0XHNPT
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|---|---|---|---|---|---|---|
| Linker Name |
Ala-Asn linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C9H14BrN3O5
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| Isosmiles |
OC([C@H](CC(N)=O)NC([C@H](C)NC(CBr)=O)=O)=O
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| InChI |
InChI=1S/C9H14BrN3O5/c1-4(12-7(15)3-10)8(16)13-5(9(17)18)2-6(11)14/h4-5H,2-3H2,1H3,(H2,11,14)(H,12,15)(H,13,16)(H,17,18)/t4-,5-/m0/s1
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| InChIKey |
NJFNIAWBACVFRG-WHFBIAKZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
324.131
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Polar area
|
138.59
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Complexity
|
329.9474732
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xlogp Value
|
-1.6692
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Heavy Count
|
18
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Rot Bonds
|
7
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Hbond acc
|
4
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker