Linker Information
General Information of This Linker
| Linker ID |
LIN0XELIB
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| Linker Name |
CN119630431A-ADC-24-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H38N4O9S2
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| Isosmiles |
O=C(N1CCOCCOCCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C1=O
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| InChI |
InChI=1S/C36H38N4O9S2/c41-29(37-23-30(42)39-28(34(45)38-24-31(43)44)22-25-10-4-1-5-11-25)16-18-48-20-21-49-19-17-40-35(46)32(50-26-12-6-2-7-13-26)33(36(40)47)51-27-14-8-3-9-15-27/h1-15,28H,16-24H2,(H,37,41)(H,38,45)(H,39,42)(H,43,44)/t28-/m0/s1
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| InChIKey |
MQXXPBONHFGVMY-NDEPHWFRSA-N
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| Pharmaceutical Properties |
Molecule Weight
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734.853
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Polar area
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180.44
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Complexity
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1564.30591
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xlogp Value
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2.6192
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Heavy Count
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51
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Rot Bonds
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21
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Hbond acc
|
10
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Hbond Donor
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4
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Each Antibody-drug Conjugate Related to This Linker