Linker Information
General Information of This Linker
| Linker ID |
LIN0XEKLS
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
MHT-71
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C38H57N7O9
|
|||||
| Isosmiles |
CC(C)C(CC(=O)CC1CC(CNC(=O)CCCCCN2C(=O)C=CC2=O)C(O)C1O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(CCN)cc1
|
|||||
| InChI |
InChI=1S/C38H57N7O9/c1-23(2)29(36(52)44-30(7-6-17-41-38(40)54)37(53)43-27-11-9-24(10-12-27)15-16-39)21-28(46)20-25-19-26(35(51)34(25)50)22-42-31(47)8-4-3-5-18-45-32(48)13-14-33(45)49/h9-14,23,25-26,29-30,34-35,50-51H,3-8,15-22,39H2,1-2H3,(H,42,47)(H,43,53)(H,44,52)(H3,40,41,54)
|
|||||
| InChIKey |
CFZCPIUDESIPQI-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
755.914
|
Polar area
|
263.35
|
||
|
Complexity
|
54
|
xlogp Value
|
0.6406
|
|||
|
Heavy Count
|
54
|
Rot Bonds
|
23
|
|||
|
Hbond acc
|
10
|
Hbond Donor
|
8
|
|||
Each Antibody-drug Conjugate Related to This Linker
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.