General Information of This Linker
Linker ID
LIN0XDJXF
Linker Name
HK40112172A+Antibody-drug conjugate (36)+Linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C23H31N5O8
Isosmiles
O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(O)=O)=O)=O)CNC(CCCN2C(CCC2O)=O)=O
InChI
InChI=1S/C23H31N5O8/c29-17(7-4-10-28-20(32)8-9-21(28)33)24-12-18(30)25-13-19(31)27-16(23(36)26-14-22(34)35)11-15-5-2-1-3-6-15/h1-3,5-6,16,20,32H,4,7-14H2,(H,24,29)(H,25,30)(H,26,36)(H,27,31)(H,34,35)/t16-,20?/m0/s1
InChIKey
JGXCVVJLDRDXIZ-DJZRFWRSSA-N
Pharmaceutical Properties
Molecule Weight
505.528
Polar area
194.24
Complexity
908.6165181
xlogp Value
-2.1319
Heavy Count
36
Rot Bonds
14
Hbond acc
7
Hbond Donor
6
Each Antibody-drug Conjugate Related to This Linker