Linker Information
General Information of This Linker
| Linker ID |
LIN0XDBYM
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| Linker Name |
MC-Val-Ala-RG-15
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C42H58N8O12S
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(CCN3CCN(CCS(=O)(O)=O)CC3)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O
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| InChI |
InChI=1S/C42H58N8O12S/c1-29(2)38(46-35(51)11-5-4-8-18-50-36(52)16-17-37(50)53)40(55)44-30(3)39(54)45-33-14-12-31(13-15-33)28-62-41(56)43-27-32-9-6-7-10-34(32)49(42(57)58)24-23-47-19-21-48(22-20-47)25-26-63(59,60)61/h6-7,9-10,12-17,29-30,38H,4-5,8,11,18-28H2,1-3H3,(H,43,56)(H,44,55)(H,45,54)(H,46,51)(H,57,58)(H,59,60,61)/t30-,38-/m0/s1
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| InChIKey |
BNFNGVMWNUEYRO-BFXRBFBZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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899.037
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Polar area
|
264.4
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Complexity
|
1972.573902
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xlogp Value
|
2.1722
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Heavy Count
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63
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Rot Bonds
|
23
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker