Linker Information
General Information of This Linker
| Linker ID |
LIN0XCGNC
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| Linker Name |
Daratumumab-I-33-0.33 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C65H91FN10O21
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| Isosmiles |
CC(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(NCCOCCOCCOCCOCCNC(C3=CC=C(OC(CCOCCOCCOCCOCCOCCOCCN)=O)C(F)=C3)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)CC5=CNC=N5)=O
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| InChI |
InChI=1S/C65H91FN10O21/c1-45(77)73-57(41-49-43-68-44-72-49)65(86)74-54(11-13-59(79)80)63(84)75-55(38-46-6-9-50(78)10-7-46)64(85)76-56(40-48-42-71-53-5-3-2-4-51(48)53)62(83)70-17-21-90-25-29-94-33-32-93-28-24-89-20-16-69-61(82)47-8-12-58(52(66)39-47)97-60(81)14-18-87-22-26-91-30-34-95-36-37-96-35-31-92-27-23-88-19-15-67/h2-10,12,39,42-44,54-57,71,78H,11,13-38,40-41,67H2,1H3,(H,68,72)(H,69,82)(H,70,83)(H,73,77)(H,74,86)(H,75,84)(H,76,85)(H,79,80)/t54-,55-,56-,57-/m0/s1
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| InChIKey |
QIAPUYMGRHDWDW-BNCXHCIVSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1367.49
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Polar area
|
421.22
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Complexity
|
3002.069304
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xlogp Value
|
0.5539
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Heavy Count
|
97
|
Rot Bonds
|
54
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Hbond acc
|
22
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker