Linker Information
General Information of This Linker
| Linker ID |
LIN0XBTNH
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| Linker Name |
NZ818359A+PR300159-B71+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H35N5O4
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| Isosmiles |
CC(C(NC(CCCC#CC1=CN=CN=C1)=O)C(N[C@@H](CCCCN(C)C)C(O)=O)=O)C
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| InChI |
InChI=1S/C23H35N5O4/c1-17(2)21(22(30)26-19(23(31)32)11-8-9-13-28(3)4)27-20(29)12-7-5-6-10-18-14-24-16-25-15-18/h14-17,19,21H,5,7-9,11-13H2,1-4H3,(H,26,30)(H,27,29)(H,31,32)/t19-,21?/m0/s1
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| InChIKey |
DDCKKVRYEBWDNO-ZQRQZVKFSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
445.564
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Polar area
|
124.52
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Complexity
|
750.2232037
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xlogp Value
|
1.4405
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Heavy Count
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32
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Rot Bonds
|
13
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Hbond acc
|
6
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker