Linker Information
General Information of This Linker
| Linker ID |
LIN0WYRIE
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| Linker Name |
CN113549127A-ADC-3-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H53N11O10S
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| Isosmiles |
CCCSC1=NC(CN2CCCC(N=N3)=CN3CCOCCOCCNC(COC(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CCCNC(N)=O)=O)=O)=O)=C(C2=O)C=N1
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| InChI |
InChI=1S/C34H53N11O10S/c1-4-17-56-33-38-18-24-26(40-33)20-44(30(24)48)11-6-7-23-19-45(43-42-23)12-14-54-16-15-53-13-10-36-27(46)21-55-34(52)41-28(22(2)3)29(47)39-25(31(49)50)8-5-9-37-32(35)51/h18-19,22,25,28H,4-17,20-21H2,1-3H3,(H,36,46)(H,39,47)(H,41,52)(H,49,50)(H3,35,37,51)/t25-,28-/m0/s1
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| InChIKey |
UBSGHTFJYVRBFB-LSYYVWMOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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807.932
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Polar area
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284.21
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Complexity
|
1531.083565
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xlogp Value
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0.0769
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Heavy Count
|
56
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Rot Bonds
|
27
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Hbond acc
|
15
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker