Linker Information
General Information of This Linker
| Linker ID |
LIN0WYKVR
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| Linker Name |
IG-L-20 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C60H83N13O21
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| Isosmiles |
C[C@H](NC(CCC1=CC=C(N2C(C=CC2=O)=O)C=C1OCCCC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CCOCC(O)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)=O)C(N[C@@H](C)C(NC3=CC=C(C=C3)COC(O)=O)=O)=O
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| InChI |
InChI=1S/C60H83N13O21/c1-38(58(88)62-39(2)59(89)63-42-18-14-40(15-19-42)36-94-60(90)91)61-45(74)21-17-41-16-20-43(73-47(76)22-23-48(73)77)27-44(41)93-25-12-13-46(75)65(4)29-50(79)67(6)31-52(81)69(8)33-54(83)71(10)35-56(85)72(11)34-55(84)70(9)32-53(82)68(7)30-51(80)66(5)28-49(78)64(3)24-26-92-37-57(86)87/h14-16,18-20,22-23,27,38-39H,12-13,17,21,24-26,28-37H2,1-11H3,(H,61,74)(H,62,88)(H,63,89)(H,86,87)(H,90,91)/t38-,39-/m0/s1
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| InChIKey |
YMQYIBXGLFEJQB-YDAXCOIMSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1322.394
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Polar area
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409.76
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Complexity
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3038.724418
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xlogp Value
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-2.7229
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Heavy Count
|
94
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Rot Bonds
|
37
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Hbond acc
|
19
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker