Linker Information
General Information of This Linker
| Linker ID |
LIN0WYIUB
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|---|---|---|---|---|---|---|
| Linker Name |
Pyridino-caproic-Val-Cit-PABC
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H45Br2N7O6
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| Isosmiles |
CC(C)C(NC(=O)CCCCCNC(=O)c1cc(CBr)nc(CBr)c1)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
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| InChI |
InChI=1S/C32H45Br2N7O6/c1-20(2)28(41-27(43)8-4-3-5-13-36-29(44)22-15-24(17-33)38-25(16-22)18-34)31(46)40-26(7-6-14-37-32(35)47)30(45)39-23-11-9-21(19-42)10-12-23/h9-12,15-16,20,26,28,42H,3-8,13-14,17-19H2,1-2H3,(H,36,44)(H,39,45)(H,40,46)(H,41,43)(H3,35,37,47)
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| InChIKey |
QVJGQRUKXGQIOV-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
783.563
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Polar area
|
204.64
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Complexity
|
47
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xlogp Value
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3.3667
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Heavy Count
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47
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Rot Bonds
|
20
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Hbond acc
|
7
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker
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