Linker Information
General Information of This Linker
| Linker ID |
LIN0WYAMX
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| Linker Name |
IG-L-47 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C62H86FN15O21
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| Isosmiles |
CN(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(O)=O)C)=O)=O)C)=O)=O)C)=O)=O)C(CN(C)C(O)CN(C(CN(C)C(CCCOC1=C(F)C(N2C(C=CC2=O)=O)=CC=C1CCC(NCC(NCC(NC(CC3=CC=CC=C3)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)C)=O
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| InChI |
InChI=1S/C62H86FN15O21/c1-68(29-49(85)69(2)30-50(86)70(3)31-51(87)71(4)32-52(88)72(5)33-53(89)73(6)34-54(90)74(7)35-55(91)75(8)36-56(92)76(9)37-57(93)77(10)38-59(96)97)46(82)17-14-24-99-61-40(18-20-42(60(61)63)78-47(83)22-23-48(78)84)19-21-43(79)64-26-44(80)65-27-45(81)67-41(62(98)66-28-58(94)95)25-39-15-12-11-13-16-39/h11-13,15-16,18,20,22-23,41,50,86H,14,17,19,21,24-38H2,1-10H3,(H,64,79)(H,65,80)(H,66,98)(H,67,81)(H,94,95)(H,96,97)
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| InChIKey |
HWJHEHCIZIOMOB-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1396.452
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Polar area
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443.87
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Complexity
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3221.065908
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xlogp Value
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-6.0322
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Heavy Count
|
99
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Rot Bonds
|
40
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Hbond acc
|
20
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker